ÚLTIMOS CINCO AÑOS
PublicacionesDos Santos RS, Guzman-Llorens D, Perez-Serna AA, Nadal A, Marroqui L. (2023)
Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human EndoC-βH1 β-cells against proinflammatory insults.
Frontiers in Immunology 14:1263926.
doi: 10.3389/fimmu.2023.1263926.
Muncke J, Andersson AM, Backhaus T, Belcher SM, Boucher JM, Carney Almroth B, Collins TJ, Geueke B, Groh KJ, Heindel JJ, von Hippel FA, Legler J, Maffini MV, Martin OV, Peterson Myers J, Nadal A, Nerin C, Soto AM, Trasande L, Vandenberg LN, Wagner M, Zimmermann L, Thomas Zoeller R, Scheringer M. (2023)
A vision for safer food contact materials: Public health concerns as drivers for improved testing.
Environment International 180:108161.
doi: 10.1016/j.envint.2023.108161.
Heindel JJ, Alvarez JA, Atlas E, Cave MC, Chatzi VL, Collier D, Corkey B, Fischer D, Goran MI, Howard S, Kahan S, Kayhoe M, Koliwad S, Kotz CM, La Merrill M, Lobstein T, Lumeng C, Ludwig DS, Lustig RH, Myers P, Nadal A, Trasande L, Redman LM, Rodeheffer MS, Sargis RM, Stephens JM, Ziegler TR, Blumberg B. (2023)
Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop.
American Journal of Clinical Nutrition S0002-9165(23)63923-1.
doi: 10.1016/j.ajcnut.2023.05.024.
Martínez-Pinna J, Sempere-Navarro R, Medina-Gali RM, Fuentes E, Quesada I, Sargis RM, Trasande L, Nadal A. (2023)
Endocrine disruptors in plastics alter β-cell physiology and increase the risk of diabetes mellitus.
American Journal of Physiology- Endocrinology and Metabolism 324(6):E488-E505.
doi: 10.1152/ajpendo.00068.2023.
Dos Santos RS, Babiloni-Chust I, Marroqui L, Nadal A. (2023)
Screening of Metabolism-Disrupting Chemicals on Pancreatic α-Cells Using In Vitro Methods.
International Journal of Molecular Sciences. 24(1):231.
doi: 10.3390/ijms24010231.
Perez-Serna AA, Dos Santos RS, Ripoll C, Nadal A, Eizirik DL, Marroqui L. (2023)
BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis.
International Journal of Molecular Sciences. 2023 Mar 16;24(6):5657.
doi: 10.3390/ijms24065657.
Babiloni-Chust I, Dos Santos RS, Medina-Gali RM, Perez-Serna AA, Encinar JA, Martinez-Pinna J, Gustafsson JA, Marroqui L, Nadal A. (2022)
G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ERα and ERβ in pancreatic beta cells.
Environment International 164:107250.
doi: 10.1016/j.envint.2022.107250.
Dos Santos RS, Medina-Gali RM, Babiloni-Chust I, Marroqui L, Nadal A. (2022)
In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic β-Cell Model.
International Journal of Molecular Sciences. 2022; 23(9):5040
doi: 10.3390/ijms23095040
Tudurí E, Soriano S, Almagro L, García-Heredia A, Rafacho A, Alonso-Magdalena P, Nadal A, Quesada I (2022)
The effects of aging on male mouse pancreatic β-cell function involve multiple events in the regulation of secretion: influence of insulin sensitivity.
J Gerontol A Biol Sci Med Sci. Sep 25:glab276.
doi: 10.1093/gerona/glab276.
Tudurí E, Soriano S, Almagro L, Montanya E, Alonso-Magdalena P, Nadal Á, Quesada I. (2022)
The pancreatic β-cell in ageing: Implications in age-related diabetes.
Ageing Res Rev. 80:101674.
doi: 10.1016/j.arr.2022.101674
García-Arévalo M, Lorza-Gil E, Cardoso L, Batista TM, Araujo TR, Ramos LAF, Areas MA, Nadal A, Carneiro EM, Davel AP. (2021)
Ventricular Fibrosis and Coronary Remodeling Following Short-Term Exposure of Healthy and Malnourished Mice to Bisphenol A.
Front Physiol. 2021 Apr 12;12:638506.
doi: 10.3389/fphys.2021.638506. eCollection 2021.
Sala E, Vived C, Luna J, Saavedra-Ávila NA, Sengupta U, Castaño AR, Villar-Pazos S, Haba L, Verdaguer J, Ropero AB, Stratmann T, Pizarro J, Vázquez-Carrera M, Nadal A, Lahti JM, Mora C. (2021)
CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.
Front Immunol. 2021 Feb 10;12:634797.
doi: 10.3389/fimmu.2021.634797. eCollection 2021.
Marroqui L, Martinez-Pinna J, Castellano-Muñoz M, Dos Santos RS, Medina-Gali RM, Soriano S, Quesada I, Gustafsson JA, Encinar JA, Nadal A. (2021)
Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated pathway.
Chemosphere Feb;265:129051.
doi: 10.1016/j.chemosphere.2020.129051
Muncke J, Andersson AM, Backhaus T, Boucher JM, Carney Almroth B, Castillo Castillo A, Chevrier J, Demeneix BA, Emmanuel JA, Fini JB, Gee D, Geueke B, Groh K, Heindel JJ, Houlihan J, Kassotis CD, Kwiatkowski CF, Lefferts LY, Maffini MV, Martin OV, Myers JP, Nadal A, Nerin C, Pelch KE, Fernández SR, Sargis RM, Soto AM, Trasande L, Vandenberg LN, Wagner M, Wu C, Zoeller RT, Scheringer M. (2020)
Impacts of food contact chemicals on human health: a consensus statement.
Environ Health. 19(1):25.
doi: 10.1186/s12940-020-0572-5.
Boronat-Belda T, Ferrero H, Al-Abdulla R, Quesada I, Gustafsson JA, Nadal A, Alonso-Magdalena P. (2020)
Bisphenol-A exposure during pregnancy alters pancreatic β-cell division and mass in male mice offspring: A role for ERβ.
Food Chemical Toxicology 145:111681.
doi: 10.1016/j.fct.2020.111681.
Quesada-Candela C, Tudurí E, Marroquí L, Alonso-Magdalena P, Quesada I, Nadal A. (2020)
Morphological and functional adaptations of pancreatic alpha-cells during late pregnancy in the mouse.
Metabolism 102, 153963.
doi: 10.1016/j.metabol.2019.153963
Legler J, Zalko D, Jourdan F, Jacobs M, Fromenty B, Balaguer P, Bourguet W, Munic Kos V, Nadal A, Beausoleil C, Cristobal S, Remy S, Ermler S, Margiotta-Casaluci L, Griffin JL, Blumberg B, Chesné C, Hoffmann S, Andersson PL, Kamstra JH. (2020)
The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds.
International Journal of Molecular Sciences 21(10):3480.
doi: 10.3390/ijms21103480.
Gibert Y, Nadal A, Sargis R eds. (2020)
Endocrine Disrupters and Metabolism.
Lausanne: Frontiers Media SA.
doi: 10.3389/978-2-88963-422-4 (ebook)
Alonso-Magdalena P, Nadal A. (2020)
The Commonly Overlooked Factor. Commentary on: «Environmental Obesogens and their Impact on Susceptibility to Obesity».
Endocrinology. 161(9):bqaa123.
doi: 10.1210/endocr/bqaa123.
Martinez-Pinna J, Marroqui L, Hmadcha A, Lopez-Beas J, Soriano S, Villar-Pazos S, Alonso-Magdalena P, Dos Santos RS, Quesada I, Martin F, Soria B, Gustafsson JÅ, Nadal A. (2019)
Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells.
Diabetologia. Sep;62(9):1667-1680.
doi: 10.1007/s00125-019-4925-y.
Esteban J, Serrano-Maciá M, Sánchez-Pérez I, Alonso-Magdalena P, Pellín MC, García-Arévalo M, Nadal Á, Barril J. (2019)
In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring.
Food Chem Toxicol. Apr;126:142-151.
doi: 10.1016/j.fct.2019.02.023.
Bru-Tari E, Cobo-Vuilleumier N, Alonso-Magdalena P, Dos Santos RS, Marroqui L, Nadal A, Gauthier BR, Quesada I. (2019)
Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes.
Scientific Reports. Jul 2;9(1):9515.
doi: 10.1038/s41598-019-45853-1.9
Soriano S, Castellano-Muñoz M, Rafacho A, Alonso-Magdalena P, Marroquí L, Ruiz-Pino A, Bru-Tarí E, Merino B, Irles E, Bello-Pérez M, Iborra P, Villar-Pazos S, Vettorazzi JF, Montanya E, Luque RM, Nadal Á, Quesada I. (2019)
Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells.
Molecular Cellular Endocrinology 479:123-132.
doi: 10.1016/j.mce.2018.09.009.
Soriano S, Gil-Rivera M, Marroqui L, Alonso-Magdalena P, Fuentes E, Gustafsson JA, Nadal A, Martinez-Pinna J. (2019)
Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception.
Scientific Reports. Jul 16;9(1):10306.
doi: 10.1038/s41598-019-46769-6.
Zoeller RT, Doan L, Demeneix B, Gore AC, Nadal A, Tan S. (2019)
Update on Activities in Endocrine Disruptor Research and Policy.
Endocrinology. Jul 1;160(7):1681-1683.
doi: 10.1210/en.2019-00166
Stahlhut RW, Myers JP, Taylor JA, Nadal A, Dyer JA, Vom Saal FS. (2018)
Exposure and Glucose-Stimulated Insulin Response in Adult Men and Women.
Journal of the Endocrine Society.
Sep 12;2(10):1173-1187.
doi: 10.1210/js.2018-00151
Marroqui L, Tuduri E, Alonso-Magdalena P, Quesada I, Nadal A, Dos Santos RS. (2018)
Mitochondria as a target of endocrine-disrupting chemicals: implications for type 2 diabetes.
Journal of Endocrinology. Aug 2. pii: JOE-18-0362.
doi: 10.1530/JOE-18-0362.
Nadal A, Fuentes E, Ripoll C, Villar-Pazos S, Castellano-Muñoz M, Soriano S, Martinez-Pinna J, Quesada I, Alonso-Magdalena P. (2018)
Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond Paracelsus?.
Journal of Steroid Biochemistry and Molecular Biology. 176:16-22.
doi: 10.1016/j.jsbmb.2017.01.014
Nuñez P, Fernandez T, García-Arévalo M, Alonso-Magdalena P, Nadal A, Perillan C, Arguelles J. (2018)
Effects of bisphenol A treatment during pregnancy on kidney development in mice: a stereological and histopathological study.
Journal of Developmental Origins of Health and Disease. 9(2):208-214.
doi: 10.1017/s2040174417000939
Gallo F, Fossi C, Weber R, Santillo D, Sousa J, Ingram I, Nadal A, Romano D. (2018)
Marine litter plastics and microplastics and their toxic chemicals components: the need for urgent preventive measures.
Environmental Sciences Europe.30(1):13.
doi: 10.1186/s12302-018-0139-z
Martinez-Pinna J, Soriano S, Tudurí E, Nadal A, de Castro F. (2018)
A Calcium-Dependent Chloride Current Increases Repetitive Firing in Mouse Sympathetic Neurons.
Frontiers in Physiology. May 14;9:508.
doi: 10.3389/fphys.2018.00508.